HEPBEST - 25MG

Tenofovir Alafenamide is an anti-hepaciviral & anti-retroviral medicine. In HIV infected patients, Hepbestis not used alone and it may combine with some other anti-retroviral drugs like Emtricitabine, cobicistat, or darunavir. At first, Hepbest is belongs to anti-retroviral (nucleoside reverse transcriptase inhibitor), now Hepbest has anti-hepaciviral property which is used against hepatitis B viral infection

Hepbest Tablet

USES

Prior usage of Hepbest tablet, used in HIV-1 infection Hepbest tablet is also indicated for the treatment of hepatitis B viral infection, by reducing the advancement of virus Hepbest used in chronic hepatitis B infection, is non-curable but it can able to prevent the viral transmission

CATEGORY

Anti-retroviral drug
Anti-hepaciviral drug

HEPBEST TABLET

The usual dosage of Hepbest tablet is, one tablet containing 25mg of Tenofovir Alafenamide should be taken as a single dose Hepbest tablet should be administered with food In creatinine clearance range <15ml/min, Hepbest is not recommended In decompensated cirrhosis: Hepbest should not be recommended Before initiating the therapy: Patients should examine HIV-1 infection for recommending combination of other anti-retroviral drugs in HIV-1 positive patients.

SIDE EFFECTS

Important adverse effects; 

Lactic acidosis or severe hepatomegaly with steatosis

Reactivation of hepatitis B viral infection in worsening condition after the therapy

Renal damage occurs

Some of undesirable effects;

Headache

Fatigue

Cough

Nausea

Back pain

Abdominal pain

Reduction in bone mineral density

Glycosuria

Creatine kinase elevation

Amylase lipase elevated.